Threshold mechanisms in acetylcholine pathway insecticides and environmental safety

Overview Previously we looked at some of the basic principles of nervous system function and how chemicals from several pesticide classes disrupt normal function.  This time we will look in detail about what we can expect for a dose-response characterization of acetylcholine pathway insecticides based upon their mode of action and properties of the nervous system.... Continue Reading →

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EPA’s Proposed Imidacloprid Exposure Limitations are Not Strong Enough

Our comment letter to EPA follows below.   OPP Docket Environmental Protection Agency Docket Center (EPA/DC), (28221T) 1200 Pennsylvania Ave. NW. Washington, DC 20460-0001   Re: Pollinator Ecological Risk Assessments: Imidacloprid Registration Review EPA-HQ-OPP-2008-0844   To whom it may concern, We would like to offer some comments on the regulatory endpoints that are proposed in... Continue Reading →

The Mechanisms of Neuro-toxic Pesticides

Agricultural pesticides have become part of the chemical landscape that we all  live in.  To be able to make intelligent decision about the use and regulation of these chemicals, it's important to understand how they work.  Almost all modern pesticides are chemicals that interfere in some way with the nervous system. The characteristics of the... Continue Reading →

Environmental Implications of Pesticides with Delayed Toxicity

The debate about the environmental safety, or lack there of, for the neonicotinoid insecticides begs us to ask what would be the characteristics of an environmentally safe or benign pesticide?  Despite a growing and flourishing organic agriculture movement, industrial agriculture is not going away any time soon.  Hence it is important to understand how to... Continue Reading →

Neonics and Bees — Political Inaction Persists Despite Mounting Evidence

Over the course of the last year, the issue of bees and the neonicotinoid pesticides has finally begun to appear in the popular press in this country.  A campaign by Friends of the Earth in the UK resulted in major garden center chains removing the neonics from their shelves in February of last year.  Early... Continue Reading →

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